The IRS recently posted its final version of the 2011 990 form, which is used by not-for-profit organizations. Significant changes to this version of the 990 are outlined in the IRS instructions, available here: http://www.irs.gov/pub/irs-pdf/i990.pdf
A recent article published in the AICPA's Journal of Accountancy also summarized the significant changes on the form. The article is available here: http://www.journalofaccountancy.com/Web/20125042.htm